Have you been feeling tired, no matter how much you sleep? Noticing a decline in your mental clarity? Struggling to recover from workouts? These could be signs of aging, hormone imbalance, or cellular inefficiency. Perhaps you've heard of regenerative therapies like sermorelin or NAD+ therapy, but aren’t sure which one fits your needs.

At Genesis Lifestyle Medicine, we specialize in helping you understand your body’s needs and match you with treatments that restore energy, vitality, and long-term health. Whether you're looking to boost growth hormone levels, improve cognitive function, or feel younger again, this guide will help you make an informed decision about which path to take.

What are sermorelin and NAD+ therapy?

Sermorelin therapy

Sermorelin is a synthetic version of a naturally occurring peptide called growth hormone-releasing hormone (GHRH). Its primary role is to stimulate your pituitary gland to produce and release more of your natural growth hormone. Unlike direct growth hormone therapy, sermorelin encourages your body to regulate growth hormone levels naturally.

This therapy is often used to combat age-related decline in growth hormone production. As a result, it supports improvements in sleep, metabolism, energy, muscle tone, and overall vitality. Sermorelin is typically administered as a daily injection and is best suited for individuals experiencing hormonal imbalances related to aging.

NAD+ therapy

Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme found in every cell of your body. It plays a crucial role in cellular energy production, mitochondrial function, and DNA repair. Unfortunately, NAD+ levels decline significantly with age and stress, contributing to fatigue, cognitive decline, slower recovery, and other signs of aging.

NAD+ therapy involves intravenous or injectable administration of NAD+ to restore optimal cellular energy. It’s widely used for enhancing brain function, improving metabolic efficiency, promoting anti-aging effects, and supporting detoxification and addiction recovery. Because it acts at the cellular level, NAD+ therapy benefits nearly every system in the body.

Choose sermorelin therapy if…

Sermorelin is ideal for individuals whose primary concern revolves around hormonal decline and the aging process. You may benefit most from this therapy if the following applies to you:

• You suspect age-related hormone decline: If you’re in your 40s, 50s, or beyond and experiencing symptoms like fatigue, weight gain, low libido, or decreased muscle mass, sermorelin can help by restoring your body’s ability to produce growth hormone.
  
• You want to improve sleep and recovery: Sermorelin has been shown to enhance deep sleep and promote better recovery after physical exertion. If you’ve been waking up tired or struggling to bounce back from workouts, this therapy may help reset your natural rhythm.
  
• You’re looking for a more natural approach to hormone support: Because sermorelin stimulates your body to produce growth hormone rather than replacing it directly, it offers a safer, more natural method of hormonal optimization with fewer long-term risks.
  
• You want to enhance lean muscle and reduce fat: Growth hormone plays a key role in body composition. If you’re working hard to gain muscle or lose stubborn fat, sermorelin may help by improving your metabolism and cellular repair mechanisms.

Choose NAD+ therapy if…

NAD+ therapy is ideal for individuals seeking full-body cellular revitalization, especially those who feel mentally and physically burned out or are dealing with chronic fatigue or brain fog. You may benefit most from this therapy if the following applies to you:

• You feel chronically fatigued or mentally foggy: If you wake up tired, struggle with energy dips throughout the day, or find it hard to focus or recall information, NAD+ therapy can help restore mental clarity and increase energy production at the cellular level.
  
• You want to slow aging and improve cellular repair: NAD+ plays a critical role in activating sirtuins, enzymes that help regulate aging and DNA repair. If your focus is on longevity, anti-aging, and cellular regeneration, NAD+ therapy may be a better choice.
  
• You’re recovering from stress, illness, or substance use: NAD+ supports detoxification and recovery. It’s often used in clinical settings to help individuals recovering from substance abuse, chronic illness, or long-term stress that has depleted cellular reserves.
  
• You want whole-body energy support: Unlike therapies that target hormones, NAD+ enhances cellular energy in every system, from your brain and muscles to your heart and immune system. If you want a systemic energy boost, NAD+ may be right for you.

Still unsure? Let Genesis Lifestyle Medicine guide you

Choosing between sermorelin and NAD+ for your hormone therapy ultimately depends on your symptoms, goals, and health history. Some people may even benefit from a combination of both therapies, as they target different aspects of aging and vitality. At Genesis Lifestyle Medicine, our experienced medical team takes a personalized approach to wellness. We evaluate your current health, lifestyle, and concerns to create a customized treatment plan tailored to your needs.

Whether you’re looking to boost your natural hormone levels with sermorelin or revitalize your cells with NAD+, you’ll be supported every step of the way. Schedule your consultation today and take the first step toward feeling like yourself again.